Comparing Treatments for Vertical Bone Defects: Autografts, Demineralised bone matrix, and Demineralised bone matrix with I-PRF.

Comparative evaluation of the treatment outcomes for intrabony vertical defects by using intra oral osseous autograft, demineralized bone matrix alone and a combination of demineralized bone matrix and injectable platelet rich fibrin - a clinical and radiographic study. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/085890

Enrollment

Registered

2025-04-29

Start date

Unknown

Completion date

Unknown

Last updated

2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Osseous bone graft: In the test group, the intrabony vertical defect will be treated using demineralized bone matrix (DBM) as the grafting material. DBM will be carefully placed into th

Eligibility

Inclusion criteria

Inclusion criteria: 1.Presence of periodontitis with vertical intrabony defect having probing pocket depth PPD greater than or equal to 5 mm, radiographic defect depth greater than or equal to 3mm after phase I therapy (scaling and root planning). 2. Absence of any anatomical limitations 3. Patient willing to undergo surgery and ready to give written consent.

Exclusion criteria

Exclusion criteria: 1 Patients with systemic diseases, smokers and pregnant women. 2.Individuals with unacceptable oral hygiene. 3.Patients contraindicated for periodontal surgery. 4.Patients undergone periodontal therapy for past 6 months.

Design outcomes

Primary

Measure	Time frame
i.Plaque index ii. Gingival index iii.Probing pocket depth (PPD) in mm. iv. Relative clinical attachment level (RCAL) in mm is measured from the fixed marked point at apical level of customized acrylic stents to the base of pocket with grooves to ensure a reproducible placement of a periodontal (UNC 15) probe. v. Bleeding on probing (Ainamo and Bay 1976) vi.Radiographic measurements. Radiographic measurements will be carried out on intra oral periapical radiographs by paralleling technique with grid (having 1 mm compartments) Timepoint: Baseline three months six months	—

Measure

Time frame

i.Plaque index ii. Gingival index iii.Probing pocket depth (PPD) in mm. iv. Relative clinical attachment level (RCAL) in mm is measured from the fixed marked point at apical level of customized acrylic stents to the base of pocket with grooves to ensure a reproducible placement of a periodontal (UNC 15) probe. v. Bleeding on probing (Ainamo and Bay 1976) vi.Radiographic measurements. Radiographic measurements will be carried out on intra oral periapical radiographs by paralleling technique with grid (having 1 mm compartments) Timepoint: Baseline three months six months

—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr Pooja Singh

SMBT Dental College and Hospital

drpsrakhewar@gmail.com9370017343

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026