A comparison of how quickly patients wake up after stopping of sevoflurane anaesthesia when different amount of fresh gas flow (4l/min and 0.8l/min ) used during waking up phase , while the lower gas flow is used during maintenance phase of anaesthesia

Comparison The Emergence Time After Discontinuation Of Sevoflurane With Fresg Gas Flo w 4L/min and 0.8L/min During Emergence While in Maintanence Phase The Fresh Gas Flow is kept at 0.8L/min - NIL

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/085880

Enrollment

Registered

2025-04-29

Start date

Unknown

Completion date

Unknown

Last updated

2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K929- Disease of digestive system, unspecified

Interventions

Intervention1: Sevoflurane: FGF will be increased to 4L/min and sevoflurane will be discontinued at the last skin stitch at the end of surgery and time of discontinuation o

inhalation , total duration

depends on the duration of surgery Control Intervention1: Sevoflurane: FGF will be continued at 0.8L/min during emergence and sevoflurane will be discontinued 20 minutes prior to last skin stitch

depends on the duration of surgery

Eligibility

Inclusion criteria

Inclusion criteria: Patient undergoing surgery under General Anaesthesia with surgery hour more than 1 hour and using cuffed Endotracheal Tube. Patient with ASA status I, II and III. Patient weight between 30 to 80 kgs

Exclusion criteria

Exclusion criteria: 1.Patients refusing in taking part in the study 2.Neurological surgeries 3.Post operative patient who remain intubated or require elective ventilation 4.Patient of acute alcohol intoxication 5.Patient of diabetic keto acidosis

Design outcomes

Primary

Measure	Time frame
Primary objective: Comparing the emergence time after discontinuation of sevoflurane with fresh gas flow of 4l/min and 0.8l/min during emergence while in maintenance phase the fresh gas flow is kept at 0.8l/min Timepoint: 0 minutes to 20 minutes	—

Secondary

Measure	Time frame
1. To compare time of eye opening after discontinuation of sevoflurane in both the groups 2. To compare time of spontaneous movement after discontinuation of sevoflurane in both the groups Timepoint: 0 minutes to 20 minutes;1. To compare time of eye opening after discontinuation of sevoflurane in both the groups 2. To compare time of spontaneous movement after discontinuation of sevoflurane in both the groups Timepoint: 0 minutes to 20 minutes	—

Measure

Time frame

1. To compare time of eye opening after discontinuation of sevoflurane in both the groups 2. To compare time of spontaneous movement after discontinuation of sevoflurane in both the groups Timepoint: 0 minutes to 20 minutes;1. To compare time of eye opening after discontinuation of sevoflurane in both the groups 2. To compare time of spontaneous movement after discontinuation of sevoflurane in both the groups Timepoint: 0 minutes to 20 minutes

—

Countries

India

Contacts

Public ContactDR SHELVI PATEL

PRAMUKH SWAMI MEDICAL COLLEGE, BHAI KAKA UNIVERSITY

shelvipatel0@gmail.com9033272205

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026