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comparing effects of magnesium sulphate nebulization and lignocaine nebulization in reducing postoperativ sore throat, hoarseness of voice and cough in patients undergoing general anaesthesia

Comparative study of Magnesium sulphate nebulization and Lignocaine nebulization in prevention of postoperative sore throat (POST), Hoarseness of voice and Cough in patients undergoing general anaesthesia - NIL

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/085866
Enrollment
90
Registered
2025-04-28
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical Health Condition 2: O- Medical and Surgical

Interventions

Intervention1: Nebulization with magnesium sulphate 250mg dilated with 4ml NS (6.25%): To see the reduction in incidence and severity of postoperative sore throat,cough and hoarseness of voice in pati

Sponsors

Department of anaesthesiology JLN medical college
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1)patients undergoing general anaesthesia in supine position. 2)duration of surgery up to 3 hours 3)ASA physical status 1&2

Exclusion criteria

Exclusion criteria: 1)ASA class 3 and above 2)Mallampatti grades more than 2 3) any psychiatric disorders and history of epilepsy 4)neurological patients with raised intracranial pressure 5) patients with known CAD and IHD 6)pregnancy 7) patients sensitive or allergic to study drug.

Design outcomes

Primary

MeasureTime frame
To assess incidence and severity of postoperative sore throat, hoarseness of voice and cough.Timepoint: To monitor effects immediately after extubation followed by every 2nd hourly till 6th hours thereafter every 12 hours and 24 hour postoperative.

Secondary

MeasureTime frame
Haemodynamic changes HR,SBP,DBP,MAP & SPO2 Side effectsTimepoint: Hemodynamic monitoring in 1) prenebulization 2)Preinduction 3)postoperative immediately followed by 2nd hourly till 6th hour & 12th hourly & 24th hour.

Countries

India

Contacts

Public ContactDr Veena Patodi

JLN Medical college Ajmer, Rajasthan

veenapatodi@gmail.com9414008276

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026