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Helping gums heal: comparing two mouthwashes for treating plaque-induced gum inflammation

Evaluation of plaque control efficacy of chlorhexidine plus hyaluronic acid mouthrinse compared to chlorhexidine mouthrinse: a double blinded randomised controlled clinical trial. - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/085854
Enrollment
36
Registered
2025-04-28
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K050- Acute gingivitis

Interventions

Intervention1: chlorhexidine plus hyaluronic acid mouthrinse: use of 10ml undiluted solution twice daily for 4 weeks Control Intervention1: chlorhexidine mouthrinse: use of 10ml undiluted solution twi

Sponsors

NIL
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Age 18-22 years Systemically healthy Have more than 20 natural teeth. Diagnosis of biofilm-induced gingivitis of an intact periodontium. Absence of supra- or subgingival calculus detected visually or by using a periodontal probe, and perform regular tooth brushing.

Exclusion criteria

Exclusion criteria: Current use of any type of mouthwash. Smoking habit, presence of active caries. Ongoing orthodontic treatment (including post-treatment retainers). Periodontal treatment within the past 6 months and a diagnosis of periodontitis. Use of antibiotics within the past 4 months or requirement for antibiotic prophylaxis. Systemic or topical nonsteroidal anti-inflammatory drug treatment for the past 4 months. Pregnancy or lactation, history of heart valve replacement, and known intolerance or allergy to mouth rinses.

Design outcomes

Primary

MeasureTime frame
Reduction in Plaque index, Gingival Index, Gingival Bleeding IndexTimepoint: baseline, 2 weeks, 4 weeks

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactDr Srishty Goyal

Kalinga Institute Of Dental Sciences

srishtygoyal575@gmail.com7060128287

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026