Health Condition 1: K068- Other specified disorders of gingiva and edentulous alveolar ridge
Conditions
Interventions
Intervention1: Concentrated Growth Factor (CGF) with periodontal dressing after gingival depigmentation.: Concentrated Growth Factor (CGF) is an autologous platelet concentrate, derived from a patient
Sponsors
AJ Institute Of Dental Sciences
Eligibility
Inclusion criteria
Inclusion criteria: . 1. Males and females aged between 18 and 45 years. 2. Subjects with gingival pigmentation score of 2 and 3 (DOPI) 3. Systemically healthy individuals with plaque index score of less than 1, gingival index score of less than 1, thick gingival biotype, less than 2 mm of attached gingiva only will be recruited for this study. 4. Subjects with good oral hygiene and are able to perform appropriate tooth brushing following instructions of the investigators. 5. Subjects who understand the purposes of the trial and are capable of making an independent decision to comply with trial requirements 6. Subjects who are able to visit their hospitals in accordance with the trial schedule
Exclusion criteria
Exclusion criteria: 1. Subjects with gingival recession. 2. Subjects with thin gingival phenotype. 3. Subjects on antibiotic or anti-inflammatory drugs for past 3 months. 4. Subjects who have undergone periodontal surgery in the past 6 months. 5. Subjects with a habit of smoking/tobacco chewing. 6. Subjects with coexisting disorders of the kidney, liver, blood and/or circulatory system, diabetes, mental or consciousness disorder and malignant tumour (Grade 2 or above) 7. Subjects who are either pregnant, possibly pregnant or breast-feeding, or who hope to become pregnant during the period of the trial. 8. Subjects with a previous history of hypersensitivity to a drug.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To evaluate and compare the effectiveness of concentrated growth factor membrane bandage and periodontal dressing after gingival depigmentationTimepoint: 3 days, 7 days, 14 days and 21 days | — |
Secondary
| Measure | Time frame |
|---|---|
| To evaluate the pain perception among the subjects in the concentrated growth factor group and periodontal dressing groupTimepoint: 3 days, 7 days | — |
Countries
India
Contacts
Public ContactDevanarayanan Nampoothiri
AJ Institute Of Dental Sciences
Outcome results
None listed