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To find if the amount of a certain protein called IRK3 are related to the defense system of the body for being overactive in people with severe lung conditions known as ARDS

To correlate elevated IRAK3 levels and the inflammatory profiles of ARDS patients - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/04/085806
Enrollment
46
Registered
2025-04-28
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: J960- Acute respiratory failure

Interventions

Intervention1: Nil: Nil Intervention2: Nil: Nil Intervention3: Nil: Nil Control Intervention1: NIL: NIL

Sponsors

CSIR Institute of Genomics and Integrative Biology IGIB
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1 Patients aged 18 years or older will be included as ARDS primarily affects adults 2 Diagnosis of ARDS Only patients diagnosed with ARDS according to the Berlin criteria with suspected or documented Pneumonia infection in blood sputum and or BAL culture will be included in the study 3 Consent Patients or their legally authorized representatives must provide informed consent to participate in the study

Exclusion criteria

Exclusion criteria: 1 Patients receiving corticosteroid treatment 2 Patients with chronic obstructive pulmonary disease asthma ILD Emphysema or IPF 3 Diabetic patients 4 Immunosuppressive Conditions 5 Patients with Platelet count less than 20000 per microlitre and INR less than one and half 6 Patients with lung cancer existing or with history of Tuberculosis 7 Patients who has gone through lung transplant 8 Patients with pulmonary hypertension 9 Patients with Fungal infection

Design outcomes

Primary

MeasureTime frame
Cytokine Profiling and Immune PhenotypesTimepoint: The day of Onset of ARDS

Secondary

MeasureTime frame
Elevated IRAK3 Expression in Immune Suppressive GroupTimepoint: The day of Onset of ARDS

Countries

India

Contacts

Public ContactDr Deepak Govil

CSIR Institute of Genomics and Integrative Biology IGIB

krishnenduind@gmail.com9051410911

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026