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A cross sectional study on loss of x chromosomes in cancer patients

An observational study to estimate the prevalence of mLOX in women with hematological and solid malignancies - mLOX study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/04/085799
Enrollment
100
Registered
2025-04-28
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: D728- Other specified disorders of whiteblood cells

Interventions

None listed

Sponsors

Armed Forces Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All diagnosed patients with multiple myeloma as per IMWG criteria are eligible for inclusion

Exclusion criteria

Exclusion criteria: premature ovarian failure turner females known sex chromosome disorders hormone replacement therapy history

Design outcomes

Primary

MeasureTime frame
To estimate mosaic loss of X chromosome in women with hematological and solid malignanciesTimepoint: Cross sectional study Single time point evaluation—

Secondary

MeasureTime frame
to explore association between mLOX & age at onset of malignancies To explore the association between mLOX age of menarche menopause in different malignanciesTimepoint: baseline—

Countries

India

Contacts

Public ContactUday Yanamandra

Armed Forces Medical College

udayj2yanamandra@gmail.com8195035551

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026