Health Condition 1: M321- Systemic lupus erythematosus withorgan or system involvement
Conditions
Interventions
Control Intervention1: NIL: NIL
Sponsors
Topiwala national medical college
Eligibility
Inclusion criteria
Inclusion criteria: Patient of SLE as per ACR/EULAR 2019 classification criteria10 Diagnosed as a case of MAS as per one of the three above-mentioned criteria Diagnosed to have MAS between 2004 to 2024
Exclusion criteria
Exclusion criteria: Unclear diagnosis of MAS (i.e. not satisfying either of the three mentioned criteria) MAS because of causes other than SLE disease activity
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Resolution of MAS: Defined by clinical improvement and normalization of laboratory markers (ferritin, liver enzymes, blood counts) after treatment. Time to Resolution: Duration from diagnosis of MAS to clinical and laboratory resolution.Timepoint: Since it s retrospective, time points can be based on clinical records: 1.Baseline: At MAS diagnosis (clinical presentation and lab abnormalities). 2.Early Response: Within 7 days of initiating treatment. 3.Intermediate Response: 2 4 weeks after treatment initiation. 4.Final Outcome: At 3 months post-diagnosis or last follow-up. | — |
Secondary
| Measure | Time frame |
|---|---|
| Secondary Outcomes for MAS in SLE Study 1. Clinical Outcomes 2. Laboratory Outcomes 3. Treatment Outcomes 4. Long-Term OutcomesTimepoint: Baseline- at diagnosis Early response -7-14 days Intermediate- at 4 weeks Final outcome-4months Extended followup-6-12months | — |
Countries
India
Contacts
Public ContactDr Kavyasree
Topiwala National Medical College
Outcome results
None listed