Assessment of antioxidant effect of Grapeseed extract in root canal therapy in children

Antioxidant Efficacy of the Grape Seed Extract as an Intracanal Medicament during Root Canal Preparation in Primary Teeth - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/085729

Enrollment

Registered

2025-04-28

Start date

Unknown

Completion date

Unknown

Last updated

2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K041- Necrosis of pulp

Interventions

Intervention1: Pure Grapeseed extract powder: Pure grapeseed extract powder will be mixed with propylene glycol and paste will be inserted in the canal in primary teeth and the study will be conducted

Eligibility

Inclusion criteria

Inclusion criteria: Child patients with chronic irreversible pulpitis

Exclusion criteria

Exclusion criteria: Medically compromised children Developmental defects/ hypoplastic molars , resorption and mobility

Design outcomes

Primary

Measure	Time frame
Antioxidant efficacy of the Grape Seed Extract (GSE), comparison of efficacy with calcium hydroxide and ChlorhexidineTimepoint: samples will be collected at baseline and at one week	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr GAURI KALRA

Manav Rachna Dental College

drgauri_dentist@yahoo.co.in9910329898

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026