to check effect of commercially available toothpaste on gum disease in orthodontic patients

A randomized clinical trial to evaluate the efficacy of a commercially available antiplaque toothpaste on gingival health in orthodontic patients over four months - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/085714

Enrollment

Registered

2025-04-28

Start date

Unknown

Completion date

Unknown

Last updated

2026-09-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K051- Chronic gingivitis

Interventions

Intervention1: pepsodent expert gum care: commecially available antiplaque toothpaste containing zinc citrate Control Intervention1: colgate strong teeth: commercially available plain fluoridated toot

Eligibility

Inclusion criteria

Inclusion criteria: who can read and write in English Patients who plan to undergo fixed orthodontic therapy Patients with moderate to severe gingivitis

Exclusion criteria

Exclusion criteria: Patients with systemic conditions Smokers/ pregnant or lactating women Patients with Advanced periodontal conditions

Design outcomes

Primary

Measure	Time frame
plaque index, gingival index, bleeding on probingTimepoint: baseline, 2 weeks, 8 weeks, 16 weeks	—

Secondary

Measure	Time frame
matrix metalloproteinases 8 levels, myeloperoxidase levels in saliva, total colony forming units from plaqueTimepoint: baseline, 16th week	—

Countries

India

Contacts

Public ContactDr Jothi Varghese

Manipal College of Dental Sciences

jothi.v@manipal.edu9845208512

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Sep 19, 2026