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To evaluate carbonic anhydrase VI concentration, activity and streptococcus mutans level from the saliva of preschool children with white spot lesions

Salivary carbonic anhydrase VI as a biomarker for caries susceptibility and its associated streptococcus mutans of white spot lesions in pre school children - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/04/085684
Enrollment
20
Registered
2025-04-25
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Nil: Nil Control Intervention1: NIL: NIL

Sponsors

Reshma James
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Healthy children of 3-6 years of age from either gender. 2. Children with no caries lesions. 3. Children with active white spot lesions anterior teeth 4. Parents giving consent for the study

Exclusion criteria

Exclusion criteria: 1. Children who received fluoride topical application /remineralizing agents during last 3 months. 2. Children who were on antibiotic therapy within past months. 3. Children with special health care needs. 4. Children with missing teeth, filled teeth due to caries and cavitated lesions and any associated pathology of tooth

Design outcomes

Primary

MeasureTime frame
carbonic anhydrase concentration and activity and streptococcus mutans level in salivaTimepoint: 2 weeks—

Secondary

MeasureTime frame
NILTimepoint: NIL—

Countries

India

Contacts

Public ContactReshma James

Rajarajeswari dental college and hospital

shaanrathna@gmail.com9845581779

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026