Health Condition 1: C00-D49- Neoplasms Health Condition 2: D648- Other specified anemias
Conditions
Interventions
Intervention1: umbelical cord blood transfusion: Transfusion of cross checked and cross matched Umbelical cord Blood of 100 ml Once only in 7 days
Control Intervention1: Packed cell transfusion: Trans
Sponsors
Aloke Ghosh Dastidar
Eligibility
Inclusion criteria
Inclusion criteria: Persistent Grade 2 or higher hematological toxicities after chemotherapy or radiotherapy. Toxicities will be assessed by EORTC CTCAE criteria and RTOG Radiation Toxicity Grading Any of the followings - a)Hemoglobin lesser than 10 gm/dl. b)Total leucocyte count lesser than 3000/cumm. c)Absolute neutrophil count lesser than 1500/cumm. d)Platelet count lesser than 75000/cumm.
Exclusion criteria
Exclusion criteria: i)Patients who have received growth factors, such as G-CSF, GM-CSF, erythropoietin, thrombopoetin within one week. ii)Hematological toxicities due to causes other than chemotherapy or radiotherapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Increase in Hemoglobin LevelsTimepoint: at 3 days, 7 days and 3 weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| increase in ANC levelsTimepoint: at 3 days, 7 days and 3 weeks;increase in platelet levelsTimepoint: at 3 days, 7 days and 3 weeks | — |
Countries
India
Contacts
Public ContactAloke Ghosh Dastidar
Institute of PostGraduate Medical Education & Research
Outcome results
None listed