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Impact of heart valve angle on the outcome of procedures done for a heart attack

Relationship between posterior mitral leaflet coaptation angle and severity of ischemic mitral regurgitation using echocardiography - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/04/085673
Enrollment
78
Registered
2025-04-25
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I340- Nonrheumatic mitral (valve) insufficiency

Interventions

Intervention1: Nil: Nil

Sponsors

Kasturba Medical College Manipal, Manipal Academy of Higher Education
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Individuals 1. Aged more than 18 years 2. Diagnosed with myocardial infarction 3. Have undergone Percutaneous transluminal coronary angioplasty 4. Has moderate or greater Mitral regurgitation (Venacontracta width greater than 3mm, ROA greater than 0.2cm2, Regurgitant volume greater than 30 ml per beat, Regurgitant fraction greater than 30 percent) 5. On sinus rhythm

Exclusion criteria

Exclusion criteria: Individuals with 1. History of rheumatic heart disease 2. Congenital heart disease 3. Cardiomyopathies 4. Previous surgeries (valvular and other cardiac) 5. Post Myocardial infarction mechanical complications, 6. Patients with intrinsic pathology of mitral valvular apparatus.

Design outcomes

Primary

MeasureTime frame
1. To assess the correlation between the coaptation angle of the posterior mitral leaflet and the severity of ischemic mitral regurgitation (IMR) in patients after revascularization.Timepoint: Baseline and a follow up at 1 month

Secondary

MeasureTime frame
1. To determine the utility of PML angle measurement in predicting the progression of ischemic MR following revascularization during the one-month follow-up. 2. To assess the influence of LV geometry on the coaptation angle and outcomes (improvement in D.O.E or routine activity- based on NHYA functional class) in patients with ischemic mitral regurgitation following revascularization. 3. To observe the relation between mitral valve tenting area and coaptation line in predicting clinical outcomes (improvement in D.O.E/routine activity- based on NHYA functional class) and the progression of MR.Timepoint: Baseline and a follow up at 1 month

Countries

India

Contacts

Public ContactDr Mahidhar Jeedigunta

Kasturba medical college

jmahidharsarma@gmail.com9592914956

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026