Health Condition 1: I340- Nonrheumatic mitral (valve) insufficiency
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Individuals 1. Aged more than 18 years 2. Diagnosed with myocardial infarction 3. Have undergone Percutaneous transluminal coronary angioplasty 4. Has moderate or greater Mitral regurgitation (Venacontracta width greater than 3mm, ROA greater than 0.2cm2, Regurgitant volume greater than 30 ml per beat, Regurgitant fraction greater than 30 percent) 5. On sinus rhythm
Exclusion criteria
Exclusion criteria: Individuals with 1. History of rheumatic heart disease 2. Congenital heart disease 3. Cardiomyopathies 4. Previous surgeries (valvular and other cardiac) 5. Post Myocardial infarction mechanical complications, 6. Patients with intrinsic pathology of mitral valvular apparatus.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. To assess the correlation between the coaptation angle of the posterior mitral leaflet and the severity of ischemic mitral regurgitation (IMR) in patients after revascularization.Timepoint: Baseline and a follow up at 1 month | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To determine the utility of PML angle measurement in predicting the progression of ischemic MR following revascularization during the one-month follow-up. 2. To assess the influence of LV geometry on the coaptation angle and outcomes (improvement in D.O.E or routine activity- based on NHYA functional class) in patients with ischemic mitral regurgitation following revascularization. 3. To observe the relation between mitral valve tenting area and coaptation line in predicting clinical outcomes (improvement in D.O.E/routine activity- based on NHYA functional class) and the progression of MR.Timepoint: Baseline and a follow up at 1 month | — |
Countries
India
Contacts
Kasturba medical college