FindTrial
Sign In

Efficacy of 5 percent LOX Patch as an Adjuvant in the Management of Post-operative Pain following Cardiac Surgeries

Efficacy of LOX 5 percent Patch as an Adjuvant in the Management of acute post-operative pain after elective cardiac surgeries: A prospective, single-centered, double-blinded, randomized controlled Trial - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/085647
Enrollment
80
Registered
2025-04-25
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: LOX 5% Patch: . Lidocaine, a widely used local anaesthetic, has shown efficacy when administered topically for both acute and chronic pain. Its mechanism of action involves sodium chann

Sponsors

Dr Sitara Raghavan Nandyal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: patients aged between 18 and 75 years, classified as American Society of Anesthesiologists (ASA) physical status III, and undergoing elective cardiac surgeries such as coronary artery bypass grafting (CABG), valve replacement, or combined procedures.

Exclusion criteria

Exclusion criteria: patients with known hypersensitivity to lidocaine, chronic pain disorders requiring regular analgesics, history of drug abuse, psychiatric illness, significant hepatic or renal dysfunction, and patients who were hemodynamically unstable post-operatively or required prolonged overnight mechanical ventilation.

Design outcomes

Primary

MeasureTime frame
Pain assessment- VAS and NRS scoresTimepoint: 0, 1, 2, 4, 6, 12, and 24 hours post extubation—

Secondary

MeasureTime frame
Ability to perform spirometry in terms of PIFR and PEFRTimepoint: 0, 1, 2, 4, 6, 12, and 24 hours post extubation—

Countries

India

Contacts

Public ContactSitara Raghavan Nandyal

AIG Hospitals

sitaractri@gmail.com09030816425

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026