Restoration of mature permanent teeth with carious exposure by direct pulp capping using MTA and PRF

Comparative evaluation of MTA and PRF in direct pulp Capping: A randomized clinical trial in patients with carious pulp exposure. - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/085645

Enrollment

Registered

2025-04-25

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K025- Dental caries on pit and fissure surface

Interventions

Intervention1: DIRECT PULP CAPPING IN MATURE POSTERIOR TEETH USING PRF: CARIOUS PULP EXPOSURE TREATED WITH DIRECT PULP CAPPING IN MATURE POSTERIOR PERMANENT TEETH USING PRF at 6 months duration Contro

Eligibility

Inclusion criteria

Inclusion criteria: Age group of 18-45 years Maxillary and mandibular molars and premolars with deep caries involving only the occlusal surface, showing signs and symptoms of reversible pulpitis, not tender to percussion Teeth with good periodontal health No radiographic evidence of periapical changes or pathology

Exclusion criteria

Exclusion criteria: symptomatic teeth (history of spontaneous pain), radiographic evidence of periapical changes or pathology, negative response to pulp sensibility testing, periodontally compromised teeth, patients with unsatisfactory oral hygiene maintenance and pregnant and lactating females

Design outcomes

Primary

Measure	Time frame
On CBCT assessment, the probability of formation of volume of dentine bridge formed after 6 months by PRF may be higher than MTA. PRF could be a promising alternative to MTA for direct pulp capping in permanent teeth with carious exposure. Timepoint: baseline, 3 months,6 months	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactDr Rajashree Tamuli

Government Dental College and Hospital, Ahmedabad

rajashreetamuli98@gmail.com07896996264

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026