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Comparative study of two types of treatments for receding gums. One uses a natural healing gel made from the patient s own blood (called i-PRF), and the other does not. The goal is to see if adding this natural gel helps the gums heal better and cover more of the exposed tooth root.

Comparative evaluation of Coronally Advanced Flap With and without I-PRF as a root surface biomodifier in treatment of gingival recession - A Randomized controlled clinical study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/085638
Enrollment
30
Registered
2025-04-25
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Coronally Advanced Flap with I-PRF: I-PRF is a bioactive agent obtained by low-speed centrifugation, and it has the capacity to stimulate tissue regeneration. At high concentrations, PR

Sponsors

Dr Mahek S Agarwal
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Participants between 25 and 60 years. 2. Pateints having Cairo Class I or II gingival recession defects measuring greater than or equal to 3 mm 3. No Periodontal therapy in the last 6 months 4. Patients who maintained oral hygiene after Scaling and Root Planing (SRP) 5. Patients who gave informed consent for the study.

Exclusion criteria

Exclusion criteria: 1. History of any tobacco consumption 2. Any mal-positioned teeth 3. Pregnant or lactating women 4. Patient with active periodontal infection 5. Patients with systemic condition that contraindicate surgery 6. Patients allergic to Local anesthesia, chlorhexidine, antibiotics and analgesics 7. Patients on oral contraceptives.

Design outcomes

Primary

MeasureTime frame
Recession Height Width of Recession Width of Attached Gingiva Thickness of Attached Gingiva Percentage of Root CoverageTimepoint: Baseline 3 months

Secondary

MeasureTime frame
Landry Healing IndexTimepoint: 1 week 2 week

Countries

India

Contacts

Public ContactDr Monali Shah

KM Shah Dental College and Hospital

smonali2011@gmail.com9824003228

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026