Comparison of efficacy of intrathecal Dexmedetomidine versus Morphine

To compare the efficacy of intrathecal Dexmedetomidine versus intrathecal Morphine in patients undergoing Total Laparoscopic Hysterectomy under general anesthesia -A Randomized Controlled Trial. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/085627

Enrollment

Registered

2025-04-25

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N889- Noninflammatory disorder of cervixuteri, unspecified Health Condition 2: D259- Leiomyoma of uterus, unspecified

Interventions

Intervention1: Dexmedetomidine vs Morphine : route of administration- intrathecal dexmedetomidine dose- 5microgram morphine dose -200microgram duration - comparison of post-op efficacy of 2 groups i

Eligibility

Inclusion criteria

Inclusion criteria: Patients undergoing elective total laparoscopic hysterectomy under general anesthesia ASA1-2 patients

Exclusion criteria

Exclusion criteria: patient refusaL to participate duration of surgery more than 2 hours known hypersenstivity to local anaesthetic infection at site of intervention patient on anticoagulant therapy

Design outcomes

Primary

Measure	Time frame
To compare the efficacy of postoperative analgesia of intrathecal dexmedetomidine versus intrathecal morphine w.r.t duration of analgesia and post-op VAS scoresTimepoint: 1 year	—

Secondary

Measure	Time frame
1 To evaluate surgeon satisfaction score on basis of operative field and peri-operative experience as whole 2 to note any adverse event in 24hours 3 to evaluate patient satisfaction scoreTimepoint: 1year	—

Countries

India

Contacts

Public ContactDr Kartik Syal

IGMC Shimla

singhmohini28janl@gmail.com07018145735

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026