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Adult patients undergoing ultrasonography guided block for upper limb surgeries, comparing Dexamethasone and Dexmedetomidine when added to local Anaesthetics in terms of effect of Anaesthesia and duration of postoperative pain relief.

A Randomised double-blind controlled trial to compare the block efficacy and duration of post-operative analgesia between dexamethasone and dexmedetomidine as adjuvant to local anaesthesia in ultrasound-guided Supraclavicular brachial plexus block in patients undergoing upper limb orthopaedic surgeries - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/085626
Enrollment
110
Registered
2025-04-25
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S52- Fracture of forearm

Interventions

Intervention1: Local anaesthetics with 50mcg dexmedetomidine: Supraclavicular brachial plexus block will be given to adult patients undergoing upper limb orthopaedic surgeries using Local anesthetics

Sponsors

Mahatma Gandhi Institute of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. American society of Anesthesiologists (ASA) physical status I/II patients 2. Patients aged 18 years and above 3. Patients weight more than 50Kg 4. Patients of both male and female gender 5. Patients scheduled for emergency, semi emergency or elective upper limb orthopaedic (elbow, forearm and hand) surgery. 6. Patients willing to take part in the study. 7. Hemodynamically stable patient with Heart rate 60 to 85/min, MAP 60 to 75mmHg

Exclusion criteria

Exclusion criteria: 1. Patients refusing to voluntarily participate in the study 2. Patients less than 18 years of age 3. Pre-existing peripheral neuropathy of upper limb 4. Patients with Bleeding disorders 5. Patients with infection at injection site 6. Patients with pneumothorax 7. Patients on adrenoreceptor agonist or antagonist therapy 8. ASA III and above 9. Pregnancy 10. Known hypersensitivity to the study drugs.

Design outcomes

Primary

MeasureTime frame
Duration of postoperative analgesiaTimepoint: 24 hours—

Secondary

MeasureTime frame
Onset and quality of sensory and motor block, Haemodynamic stabilityTimepoint: 3 hours—

Countries

India

Contacts

Public ContactDr LAKSHMISRAVYA KETHARI

MAHATMA GANDHI INSTITUTE OF MEDICAL SCIENCES, SEVAGRAM, WARDHA

suchetatidke@mgims.ac.in9850510019

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026