Comparison of drug with adjuvant and drug alone in scalp block in craniotomy

A comparative evaluation of scalp block using 0.5% bupivacaine with dexamethasone versus 0.5% bupivacaine alone for attenuating postoperative pain in patients undergoing supratentotial craniotomy under general anaesthesia - Nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/085614

Enrollment

Registered

2025-04-25

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: G94- Other disorders of brain in diseases classified elsewhere

Interventions

Intervention1: Scalp block for post operative analgesia in supratentorial craniotomy using bupivacaine with dexamethasone and bupivacaine alone: After skin closure bilateral subcutaneous Infiltration

Eligibility

Inclusion criteria

Inclusion criteria: Posted for elective supratentorial craniotomy BMI 18-30 Kg/m² ASA grade I-II

Exclusion criteria

Exclusion criteria: Patient refusal Known allergy to bupivacaine used in the study Patient with ASA grade III and above Glasgow Coma Score (GCS) less than 15 Hepatic, renal or cardiorespiratory failure Patients undergoing emergency procedure

Design outcomes

Primary

Measure	Time frame
To compare the efficacy and safety of bupivacaine and dexamethasone as adjuvant in scalp block for supratentorial craniotomy in terms of: Duration of postoperative analgesia. Requirement of first rescue analgesia and total number of rescue analgesics Timepoint: Evaluate on the basis of VAS score in first 24 hours postoperatively	—

Secondary

Measure	Time frame
To observe Postoperative hemodynamic parameters Timepoint: 24 hour postoperatively	—

Countries

India

Contacts

Public ContactDr Kiwi Mantan

Sardar Patel Medical College

kiwivyas@gmail.com9929092702

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026