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To see the efficacy of magnesuim sulfate in reducing the agitation in obese patients undergoing weight reduction stomach surgeries.

Efficacy of Magnesium sulfate to reduce the emergence agitation, in morbidly obese patients posted for bariatric surgery. A Randomized, double blinded, placebo controlled Trial.

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/085609
Enrollment
40
Registered
2025-04-24
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: E662- Morbid (severe) obesity with alveolar hypoventilation

Interventions

Intervention1: Magnesuim Sulfate: Magnesium Sulfate (20mg/kg/hr without loading dose in 50cc syringe), given intravenously, in the intraoperative period. Control Intervention1: Saline: Saline of equa

Sponsors

AIIMS, New Delhi.
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: American Society of Anaesthesiologists Physical status (ASAPS) 1& 2. ASAPS 3 of morbid obesity. Posted for elective bariatric surgery

Exclusion criteria

Exclusion criteria: 1. Significant comorbidity like hepatic, renal, or cardiac disease 2. Auditory impairment 3. Cognitive dysfunction 4. Substance abuse 5. Allergy to the study drug 6. Planned intensive care admission after the surgery 7. ASAPS 3 or more excluding morbid obesity

Design outcomes

Primary

MeasureTime frame
Total midazolam consumption.Timepoint: 1 hour—

Secondary

MeasureTime frame
1. Time to extubation 2. Hemodynamic changes (MAP & HR) 3. Pain scores using Visual analogue scale (VAS) 4. Total amount of rescue analgesic 5. Postoperative nausea and vomiting (PONV) 6. PACU time and 7. Adverse events Timepoint: 1 hour—

Countries

India

Contacts

Public ContactDr Tangirala Nageswara Rao

All India Institute of Medical Sciences, New Delhi.

lokeshkashyap@yahoo.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026