Comparing the efficacy of Portlant cement based material with its modification in deep caries management

Comparative evaluation of efficacy of conventional Mineral Trioxide Aggregate (MTA) and modified Mineral Trioxide Aggregate in direct pulp capping using Cone Beam Computed Tomography (CBCT)-An In-Vivo Randomized Control Trial - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/085578

Enrollment

Registered

2025-04-24

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K025- Dental caries on pit and fissure surface

Interventions

Intervention1: MTA with Nigella Sativa: Mineral Trioxide Aggregate Angelus with Nigella sativa oil 50 percentage concentration will be applied once to the tooth after caries excavation and GIC restora

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with asymptomatic permanent molar teeth . 2.Periodontally strong teeth with the diagnosis of reversible pulpitis. 3. Teeth with absence of any periapical pathology and showing a closed apex on periapical radiograph

Exclusion criteria

Exclusion criteria: 1)Tenderness on percussion 2)Prescence of periapical pathology or teeth with serous exudate from exposure site 3)Teeth with spontaneous pain 4)Teeth with excess of hemorrhage at the time of exposure

Design outcomes

Primary

Measure	Time frame
To measure the dentin bridge formation of MTA without Nigella Sativa and MTA with Nigella Sativa in Direct Pulp Capping at 3rd month and 6th month with Cone Beam Computed Tomography (CBCT Timepoint: Evaluation done at 3rd month and 6th month	—

Secondary

Measure	Time frame
NILTimepoint: NIL	—

Countries

India

Contacts

Public ContactHafeela Farhana A

Karpaga Vinayaga Institute of Dental Sciences

Selvendranmds@gmail.com9444864978

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026