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Effectiveness of chlorhexidine varnish and riboflavin in reducing oral bacteria in people with braces.

COMPARING THE EFFICACY OF RIBOFLAVIN A PHOTOSENSITISING COMPOUND AND CHLORHEXIDINE VARNISH IN CONTROLLING ORAL MICROFLORA IN ORTHODONTIC PATIENTS A RANDOMISED CONTROLLED TRIAL - Nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/085485
Enrollment
30
Registered
2025-04-24
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K026- Dental caries on smooth surface

Interventions

Intervention1: Riboflavin (vitamin B2): 0.5% riboflavin solution is prepared and given to the patient to rinse the mouth for 1 minute and further it is activated using blue LED light Intervention2: Ri

Sponsors

sobika.s
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Good general health Absence of systemic antibiotic intake at least 3 months prior to study, Under fixed orthodontic treatment Absence of oral lesions Supragingival calculus Severe malocclusion Evident dental plaque accumulation.

Exclusion criteria

Exclusion criteria: The use of mouthwashes during the study and the follow-up, Pregnancy Systemic disorders History of parafunctional and deleterious habits (tobacco chewing)

Design outcomes

Primary

MeasureTime frame
Comparing the reduction of bacterial count among the experimental groups. To find out the number of live and dead bacterias using confocal laser microscopy Timepoint: T0 - Before application of test agents T1- Immediately after application T2 - 60 days after application—

Secondary

MeasureTime frame
To assess the percentage of live and dead bacterias using confocal laser scanning microscopyTimepoint: T0,T1—

Countries

India

Contacts

Public ContactDr. Sumanth Rangarajan

Sri venkateswara dental college and hospital

drsumanthranga@gmail.com9952034634

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026