STUDY OF COMPARISON BETWEEN TWO DIFFERENT ROUTES OF DEXMEDETOMIDINE GIVEN TO PARTICIPANTS TO EVALUATE HEMODYNAMIC PARAMETERS CHANGES DURING LAPAROSCOPIC SURGERY UNDER GENERAL ANAESTHESIA.

A COMPARATIVE STUDY OF INTRAVENOUS DEXMEDETOMIDINE AND DEXMEDETOMIDINE NEBULIZATION ON HEMODYNAMIC RESPONSES TO PNEUMOPERITONEUM DURING LAPAROSCOPIC SURGERY UNDER GENERAL ANAESTHESIA. - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/085474

Enrollment

Registered

2025-04-23

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: NEBULIZATION WITH DEXMEDETOMIDINE 1 g/kg MIXED WITH 5 ML NS: NEBULIZATION WITH DEXMEDETOMIDINE 1 g/kg MIXED WITH 5 ML NS OVER 10 MINUTES BEFORE INDUCTION OF LAPAROSCOPIC SURGERY UNDER G

Eligibility

Inclusion criteria

Inclusion criteria: PATIENTS GIVING VOLUNTARY WRITTEN CONSENT ASA I AND II ELECTIVE SURGERY UNDER GENERAL ANAESTHESIA PATIENTS HAVING NORMAL AIRWAY ANATOMY HEMODYNAMIC STABLE PATIENTS WITH ALL ROUTINE INVESTIGATIONS WITHIN NORMAL LIMITS

Exclusion criteria

Exclusion criteria: PATIENTS GIVING NEGATIVE CONSENT ASA III TO V PATIENTS WITH CARDIAC AND RESPIRATORY DISORDERS EMERGENCY SURGERIES PATIENTS WITH ANTICIPATED DIFFICULT AIRWAY PATIENTS HAVING HISTORY OF ALLERGY PATIENTS ADDICTED TO NARCOTICS OR ON ANY LONG TERM BETA BLOCKERS, ANXIOLYTICS, ANTICONVULSANTS AND ANTIPSYCHOTICS SURGERIES THAT ARE CONVERTED INTO OPEN SURGERIES

Design outcomes

Primary

Measure	Time frame
TO COMPARE EFFECT OF INTRAVENOUS DEXMEDETOMIDINE AND DEXMEDETOMIDINE NEBULISATION IN ATTENUATION OF HEMODYNAMIC RESPONSES TO PNEUMOPERITONEUM DURING LAPAROSCOPIC SURGERY UNDER GENERAL ANAESTHESIATimepoint: FROM 30 MINUTES PRIOR TO INDUCTION TO 24 HOURS POST EXTUBATION.	—

Secondary

Measure	Time frame
TO STUDY ADVERSE EFFECT OF DEXMEDETOMIDINE SUCH AS BRADYCARDIA, HYPOTENSION AND ARRHYTHMIA.Timepoint: 24 HOURS POST OPERATIVE;REQUIREMENT OF INTRAVENOUS PROPOFOL INTRAOPERATIVELYTimepoint: FROM INDUCTION TO EXTUBATION;REQUIREMENT OF INTRAVENOUS FENTANYL INTRAOPERATIVELYTimepoint: FROM INDUCTION TO EXTUBATION.;ASSESSMENT OF POST OPERATIVE PAIN AND SEDATIONTimepoint: 24 HOURS POST OPERATIVE	—

Countries

India

Contacts

Public ContactDR BHAVANA RAVAL

B.J. MEDICAL COLLEGE, AHMEDABAD

drbhavanaraval@yahoo.com9426373182

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026