Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: NIL: NIL
Control Intervention1: NIL: NIL
Sponsors
DEPARTMENT OF ANAESTHESIOLOGY AND CRITICAL CAREKS HEGDE MEDICAL ACADEMY
Eligibility
Inclusion criteria
Inclusion criteria: patients aged 18-60 years scheduled for elective surgeries under general anaesthesia with direct laryngoscopy and endotracheal intubation. American Society of Anaesthesiologists(ASA-PS) I and II
Exclusion criteria
Exclusion criteria: 1. patient refusal 2. patients with known allergies to ketamine, clonidine and lignocaine 3. patients with a recent history of preoperative sore throat 4. pregnant ladies 5. patients undergoing airway and thyroid surgeries
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The outcome that is measured in this study is the reduction of post-sore throat, while comparing the drug groupsTimepoint: The time points where outcomes are checked are at 1st hour, 6th hour, 12th hour and 24th hour postoperatively. | — |
Secondary
| Measure | Time frame |
|---|---|
| 1. To compare the intubation response with the postoperative sore throat. 2. To assess the severity of emergence agitation in patients receiving intra cuff ketamine and clonidine. 3. To assess the severity of emergence agitation in patients receiving intra cuff 2% alkalinized. 4. To compare the severity of emergence agitation in two groups.Timepoint: After the surgery, the patient will be assessed for any emergence agitation such as bucking, coughing over the tube and NIBP, SpO2, and HR will be recorded every 3 minutes after giving reversal up to 6 minutes after extubation. Emergence agitation during extubation, if any, will be recorded. Post-operative sore throat will be assessed in the 1st hour, 6th hour, 12th hour, and 24th hour post extubation. Sore throat will be measured on a 4-point scale of 0 3 | — |
Countries
India
Contacts
Public ContactDr Rashmi Soori
K S Hegde Medical Academy
Outcome results
None listed