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This study looks at using a medication called dexmedetomidine in a nebulizer to help the patient to relax and reduce heart rate and blood pressure changes during laryngoscopy and intubation

Evaluation of nebulised Dexmedetomidine to attenuate hemodynamic response to laryngoscopy and endotracheal intubation - nil

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/085416
Enrollment
96
Registered
2025-04-23
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

None listed

Sponsors

Gandhi medical college
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients of ASA grade I and ASA grade II Age group 20 - 60 years MPG I and II BMI less than 35

Exclusion criteria

Exclusion criteria: Patient refusal Patients requiring more than 15 seconds for intubation or more than 1 attempts of Laryngoscopy Patients taking medicines that affect the heart rate such as clonidine,beta blockers Patients undergoing emergency surgeries will be excluded from the study

Design outcomes

Primary

MeasureTime frame
To evaluate the efficacy of nebulised Dexmedetomidine given pre- operatively to attenuate Hemodynamic response to laryngoscopy and Endotracheal intubation.Timepoint: Before laryngoscopy,After laryngoscopy,1 min,5 min,10 min After intubation—

Secondary

MeasureTime frame
To calculate total amount of Propofol used during induction of General Anesthesia & Fentanyl during surgeryTimepoint: For Propfol at baseline & for Fentanyl after 1 hr to end of surgery—

Countries

India

Contacts

Public ContactDr Jyotsna Kubre

Gandhi Medical College, Bhopal

deepeshg25@gmail.com9826842567

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026