Effectiveness of a Gel with Glucosamine and Other Ingredients in Reducing Pain from Jaw Muscle and Disc Problems A Clinical Study

Evaluation of the Effectiveness of Glucosamine and Bromelain-Trypsin-Rutoside Combination Gel in the Management of Myogenous and Disc Disorders of Temporomandibular Joint- A Randomised Clinical Trial - NIL

Status

Active, not recruiting

Phases

Phase 2Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/085392

Enrollment

Registered

2025-04-23

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M278- Other specified diseases of jaws

Interventions

Intervention1: Glucosamine and Bromelain, Trypsin, Rutoside combination gel : Glucosamine and Bromelain, Trypsin, Rutoside combination gel used as a topical gel in patients with myogeneous and disc di

Eligibility

Inclusion criteria

Inclusion criteria: Patients diagnosed with myogeneous and disc disorders of TMJ

Exclusion criteria

Exclusion criteria: 1. Patients with degenerative joint disease 2.Patients with trauma history 3. Developmental and neoplastic TMD s 4. Headache and Neuropathic disorders

Design outcomes

Primary

Measure	Time frame
Pain relief (VAS score), Mouth OpeningTimepoint: Pain relief (VAS score), Mouth Opening will be recorded at baseline, 15days and 30days	—

Secondary

Measure	Time frame
Lateral Jaw movementsTimepoint: 15 days interval for 1 month;Muscle tendernessTimepoint: 15 days interval for 1 month;ACPA QoLTimepoint: 15 days interval for 1 month	—

Countries

India

Contacts

Public ContactArvind Muthukrishnan

Saveetha Dental College and Hospitals

arvindm@saveetha.com9444303303

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026