To assess the efficacy of Vyadhi Shardula Guggulu and Simhanada Guggulu along with Rasna Dashamula Kwatha in the management of Amavata (rheumatoid arthritis).

A randomized comparative clinical trial to evaluate the efficacy of Vyadhi Shardula Guggulu and Simhanada Guggulu along with Rasna Dashamula Kwatha in the management of Amavata (rheumatoid arthritis). - Nil

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/085390

Enrollment

Registered

2025-04-23

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M958- Other specified acquired deformities of musculoskeletal system

Interventions

None listed

Eligibility

Inclusion criteria

Inclusion criteria: Patients of either gender, aged 25 to 60 years. Patients exhibiting signs and symptoms of Amavata (Rheumatoid Arthritis). Patients who fulfill the criteria of ACR/EULAR 2010 criteria (American College of Rheumatology/European League Against Rheumatism). Patients with a chronicity of less than 5 years.

Exclusion criteria

Exclusion criteria: Patients with severe crippling joint deformities. Patients with associated cardiac disease, uncontrolled diabetes mellitus, malignant hypertension, or any conditions that may interfere with the outcome of interest. Pregnant women and lactating mothers. Patients taking disease-modifying anti-rheumatic drugs (DMARDs) for rheumatoid arthritis.

Design outcomes

Primary

Measure	Time frame
Change in disease activity as measured by the DAS-28 score.Timepoint: Baseline and 8 weeks.	—

Secondary

Measure	Time frame
Changes in symptom score. Changes in the HAQ-DI score. Changes in functional capacity by assessing walking time, hand & foot grip. Changes in inflammatory markers: ESR, CRP.Timepoint: Baseline, 4 weeks, & 8 weeks	—

Countries

India

Contacts

Public ContactDr Ajay Kumar Sahu

National Institute of Ayurveda

drajaysahu@gmail.com9950708106

Outcome results