Health Condition 1: L088- Other specified local infections of the skin and subcutaneous tissue
Conditions
Interventions
Intervention1: comparing various doses of oral isotretinoin in verruca vulgaris: patients will be divided into 3 groups of which the
first group will receive oral isotretinoin at a dose of 0.4mg/kg u
Sponsors
nil
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients between 14 - 60 years with clinical diagnosis of verruca vulgaris. 2.Females of childbearing age group who have undergone sterilization (tubectomy / hysterectomy/ bilateral oophorectomy) or who agree to use dual modes of contraception, (IUCD in female and barrier method in male partner ) 3.Patient with a recurrence of verruca vulgaris.
Exclusion criteria
Exclusion criteria: 1.Pregnant females / females planning pregnancy / breastfeeding mothers. 2.Immunosuppressed individuals (HIV/patients on steroids or other immunosuppressive drugs) 3.Known hypersensitivity to synthetic / natural vitamin A.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Resolution of lesions in terms of decrease in number and size 2. Total duration of therapy Timepoint: total duration of treatment is until clearance or maximum up to 12 weeks and follow up is 4 weekly | — |
Secondary
| Measure | Time frame |
|---|---|
| assessment of adverse effects like cheilitis dryness of mouth & eyes headache nausea vomiting menstural irregularities constipationTimepoint: will be done at every follow up visit 4 weekly | — |
Countries
India
Contacts
Public ContactProf Gurvinder Pal Thami
government medical college and hospital sector 32 chandigarh
Outcome results
None listed