FindTrial
Sign In

Comparing Two Medications for Numbing the Scalp During Brain Surgery: Effects on Blood Pressure, Heart Rate, and Pain After Surgery

Comparative Study of Magnesium Sulphate Vs Dexmedetomidine as Adjuvants to Bupivacaine in Scalp Nerve Block: Effects on Intraoperative Hemodynamic Parameters and Postoperative Pain for Patients Undergoing Supratentorial Brain Tumour Craniotomy (A Prospective Randomized Comparative Study) - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/085338
Enrollment
177
Registered
2025-04-22
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: scalp nerve block: To be given at 5 points. 1. supraorbital 2.supratrochlear 3.zygomaticotemporal 4. greater occipital 5. lesser occipital to block the nerves supplying the scalp Contro

Sponsors

Mahatma Gandhi Medical College Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patient fulfilling criteria ASA Classes I/ II 2. Patient aged 18-65 years of both sexes. 3. Patients undergoing elective supratentorial craniotomy under general anaesthesia.

Exclusion criteria

Exclusion criteria: Patient with ASA CLASS III, IV & V Refusal of patient Patient with difficult surgical anatomy Patient with previous craniotomy incision Local infection at the site of injection History of allergy to opioid or local anaesthesia Inability to comprehend or participate in pain scoring system.

Design outcomes

Primary

MeasureTime frame
1. To evaluate and compare intraoperative hemodynamic parameters, including heart rate (HR), systolic blood pressure, diastolic blood pressure, and mean arterial pressure. 2. To measure and compare postoperative Visual Analogue Scale (VAS) scores. 3. To determine the time until the first request for rescue analgesia Timepoint: intraoperatively postoperatively—

Secondary

MeasureTime frame
To observe and compare the need for supplemental analgesics during surgery. To analyze and compare serum cortisol levels. To quantify the total dose of analgesics required within 24 hours. To calculate the total intraoperative dose of Inj. Propofol. To calculate the total intraoperative dose of Inj. Fentanyl. Timepoint: intraoperatively postoperatively—

Countries

India

Contacts

Public ContactSwati Gupta

Mahatma Gandhi Medical College & Hospital

drsunitakhs@yahoo.com7597053927

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026