Health Condition 1: O- Medical and Surgical
Conditions
Interventions
Intervention1: Lignocaine 2% nebulisation: A detailed pre-anaesthetic checkup will be done. Baseline
investigations will be carried out. A written informed and
valid consent will be taken after explai
Sponsors
Gandhi Medical College and Associated hospitals
Eligibility
Inclusion criteria
Inclusion criteria: Patients willing to give written informed consent Patients undergoing elective surgery requiring general anaesthesia Patients of either sex ASA Grade I & II Patients having MPG I &II Not allergic to study drug
Exclusion criteria
Exclusion criteria: Patient refusal Patients with anticipated difficult intubation Patients with HTN COPD IHD and arrhythmia History of allergy or contraindication to to study drugs Pre existing hypotension (systolic blood pressure less than 90 mmHg) Pre existing bradycardia (heart rate less than 60 beats per minute) Current use of medications affecting blood pressure or heart rate ( beta-blockers calcium channel blockers) History of gastroesophageal reflux disease (GERD) or significant oral or pharyngeal pathology ASA grade III IV V Pregnancy or breastfeeding Psychiatric patients Patients with hepatic and renal dysfunction More than 1 attempt of intubation or more than 30 seconds intubation time
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean heart rate Mean systolic blood pressure Mean Diastolic blood pressure MAP (mean arterial pressure)Timepoint: Baseline vitals T1-one minute post intubation & laryngoscopy T3-Three minute post intubation & laryngoscopy T5-Five minute post intubation & laryngoscopy T7-Seven minute post intubation & laryngoscopy T10-Ten minute post intubation & laryngoscopy | — |
Secondary
| Measure | Time frame |
|---|---|
| Proportion of cases with side effectsTimepoint: 10 minutes post intubation | — |
Countries
India
Contacts
Public ContactDr Rajni Thakur
Gandhi medical college and Associated Hamidia Hospitals Bhopal M.P
Outcome results
None listed