Action of glucosamine sulfate powder on gum health in gum disease patients.

Comparative evaluation of host modulatory effects of ORTHOBOON Glucosamine sulfate plus Collagen plus Vitamin C as an adjunct to Non-Surgical Periodontal Therapy in the management of chronic periodontitis: A randomized controlled clinical trial. - NIL

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/085294

Enrollment

Registered

2025-04-21

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K053- Chronic periodontitis

Interventions

Intervention1: Glucosamine sulfate, Collagen and Vitamin C: subjects will undergo phase I therapy, followed by 500 mg of host modulating agent orally in powder form thrice daily for 30 days. Subjects

Eligibility

Inclusion criteria

Inclusion criteria: Subjects between age groups of 20 and 60 years, subjects with stage II grade A periodontitis, systemically healthy subjects and those willing to give informed consent and willing to follow the protocol of the study.

Exclusion criteria

Exclusion criteria: 1. Subjects receiving diuretics, steroids and oral contraceptives. 2. Subjects with allergies to materials used in the study. 3. Current or former smokers. 4. Pregnant or lactating women.

Design outcomes

Primary

Measure	Time frame
1. To evaluate the efficacy of host modulating agent as an adjunt to scaling and root planing in the non-surgical management of patients with chronic periodontitis. 2. To evaluate the efficacy of scaling and root planing in the non-surgical management of patients with chronic periodontitis. 3. To compare the efficacy of host modulating agent as an adjunct to non-surgical therapy in the management of patients with chronic periodontitis.Timepoint: Baseline and after 30 days	—

Measure

Time frame

1. To evaluate the efficacy of host modulating agent as an adjunt to scaling and root planing in the non-surgical management of patients with chronic periodontitis. 2. To evaluate the efficacy of scaling and root planing in the non-surgical management of patients with chronic periodontitis. 3. To compare the efficacy of host modulating agent as an adjunct to non-surgical therapy in the management of patients with chronic periodontitis.Timepoint: Baseline and after 30 days

—

Secondary

Measure	Time frame
The clinical parameters evaluated were, namely, bleeding index (BI), gingival index (GI), probing pocket depth (PPD) and clinical attachment loss (CAL).Timepoint: Baseline and after 30 days	—

Countries

India

Contacts

Public ContactDr Amruta Mahajan

Terna Dental College, Navi Mumbai

dramruta1211@gmail.com7715866553

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026