Extended CT angiography trial for etiological diagnosis of acute ischemic stroke

Extended CT angiography to diagnose cardiac etiology of acute ischemic stroke (ExtenCT) - ExtenCT

Status

Recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/085285

Enrollment

540

Registered

2025-04-21

Start date

Unknown

Completion date

Unknown

Last updated

2026-03-02

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: I639- Cerebral infarction, unspecified

Interventions

Intervention1: extended CTA: Standard of care AND Extended CTA (eCTA) with expansion of image acquisition 6cm caudally below the carina, done at admission Control Intervention1: standard CTA: Standard

Eligibility

Inclusion criteria

Inclusion criteria: Age more than 18 years Acute ischemic stroke or transient ischemic attack patients presenting within 24 hours of symptom onset or last known well

Exclusion criteria

Exclusion criteria: pregnancy, mRS more than 2, contraindication to iodinated contrast administration, previous disorders that may confound the neurological status interpretation

Design outcomes

Primary

Measure	Time frame
Detection rate of a cardio-aortic thrombus by intervention arm compared to the control armTimepoint: 4 weeks	—

Secondary

Measure	Time frame
Time to stroke etiology diagnosisTimepoint: 4 weeks;Reclassification of stroke etiologyTimepoint: 4 weeks;Change of stroke managementTimepoint: 4 weeks;Significant additional diagnosisTimepoint: 4 weeks	—

Countries

India

Contacts

Public ContactDr Ayush Agarwal

AIIMS, New Delhi

ayushthetaurian@gmail.com08193900444

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Mar 14, 2026