To compare the effect of two adjuvant drugs via regional anaesthesia in patients undergoing upper limb surgeries

Comparative study between magnesium sulphate versus dexamethasone as an adjuvant to 0.5 percent bupivacaine in supraclavicular brachial plexus block. - NIL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/085255

Enrollment

Registered

2025-04-21

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Magnesium Sulphate: Patients will be given 28ml bupivacaine 0.5% with 1ml of 50% magnesium sulphate(500mg) with 1ml normal saline via supraclavicular brachial plexus block Control Inter

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade 1 and 2 fit patients. Patients aged between 18-60 years of age. Both male and female gender. Patients posted for upper limb surgeries below shoulder. Hemodynamically stable patients with all routine investigations within normal limits. Written informed consent from the concerned patients.

Exclusion criteria

Exclusion criteria: Patients who are not willing to participate in the study. Patients with ASA grade 3 and above physical status. Patients who are aged more than 60 years and less than 18 years of age. Patients with known allergy to the study drugs. Patients who are posted for emergency procedures. Patients with bleeding disorders and those on anticoagulant therapy. Infection at site of block. Neuro deficit involving brachial plexus. Pregnant women. Patients with psychiatric, neurological, neuromuscular or cardiovascular disease or impaired hepatic or renal function.

Design outcomes

Primary

Measure	Time frame
To compare and study the onset and duration of sensory and motor blockade of magnesium sulphate and dexamethasone as an adjuvant to 0.5% Bupivacaine in supraclavicular brachial plexus blockTimepoint: The sensory block will be evaluated by pin prick sensation and motor block will be assessed with the help of modified bromage scale after injection of study drugs. Vital parameters will be monitored every 5 mins for first 15 mins and every 15 mins till the end of surgery	—

Measure

Time frame

To compare and study the onset and duration of sensory and motor blockade of magnesium sulphate and dexamethasone as an adjuvant to 0.5% Bupivacaine in supraclavicular brachial plexus blockTimepoint: The sensory block will be evaluated by pin prick sensation and motor block will be assessed with the help of modified bromage scale after injection of study drugs. Vital parameters will be monitored every 5 mins for first 15 mins and every 15 mins till the end of surgery

—

Secondary

Measure	Time frame
To compare the duration of post operative analgesia in both study groups & observe any side effects of both the drugsTimepoint: Duration of analgesia will be assessed post surgery & time to rescue analgesia will be assessed 2 hourly after surgery until intervention is required	—

Countries

India

Contacts

Public ContactDr Chhaya Suryawanshi

Dr.D.Y.Patil Medical College, Hospital and Research Centre

chhayasuryawanshi@gmail.com9922888201

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026