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Effect of Nano curcumin gel and chlorhexidine gel on the gum health growth of bacteria and implant screw loosening

Comparative evaluation of the effect of nano-curcumin gel versus 1 percent chlorhexidine gel placed inside the implant fixture on peri-implant soft tissue parameters, bacterial count and prosthetic screw loosening in patients rehabilitated with implant supported fixed prosthesis A one year randomized controlled clinical study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/085252
Enrollment
45
Registered
2025-04-21
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K084- Partial loss of teeth

Interventions

Intervention1: Nano Curcumin gel: The gel will be introduced into the implant fixture space using a syringe with needle only once at the time of prosthesis delivery and will be recalled for evaluation

Sponsors

Sejal Jain
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with at-least one missing teeth Patients in whom Screw-mentable and/or screw-retained prosthesis is to be placed Patients able to provide consent

Exclusion criteria

Exclusion criteria: Patients with systemic diseases or metabolic disorders if any which are contraindicated for implant placement. Patients who give History of Allergy to nano-curcumin or chlorhexidine. Patients in whom cement-retained prosthesis is to be placed Patients is currently a smoker or quit smoking in less than one year. Patients addicted to drugs, alcohol or tobacco in any form Pregnant and lactating patients Patients in whom bone grafting is indicated along with the placement of implants. Patients who have received or are on chemotherapy/radiotherapy or drugs that interfere with implant integration Patients with any systemic conditions that can impact gingival health Patients with heavy occlusion or bruxism

Design outcomes

Primary

MeasureTime frame
1 Peri implant soft tissue parameters Periodontal probing depth Bleeding on probing and Recession 2 Microbial count 3 Screw loosening Timepoint: Base line 3 and 12 months

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactDr Rajesh Sethuraman

KM Shah Dental College and Hospital

rajeshsethu77academics@gmail.com9725038434

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026