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EFFICACY OF DEXAMETHASONE 4 mg vs DEXMEDITOMINDINE 0.4 mcg/Kg as an adjuvant with ROPIVACAINE 0.375% IN ADDUCTOR CANAL BLOCK AS POST OPERATIVE PAIN MANAGEMENT IN KNEE SURGERIES

A COMPARITIVE STUDY OF USG GUIDED ADDUCTOR CANAL BLOCK USING DEXAMETHASONE 4mg VERSUS 0.3mcg/kg DEXMEDITOMIDINE AS AN ADJUVANT TO ROPIVACAINE 0.375% FOR POSTOPERATIVE ANALGESIA IN PATIENTS UNDERGOING KNEE SURGERIES UNDER SPINAL ANAESTHESIA - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/085222
Enrollment
56
Registered
2025-04-21
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: M179- Osteoarthritis of knee, unspecified Health Condition 2: M179- Osteoarthritis of knee, unspecified

Interventions

Intervention1: Dexamethasone 4mg as an adjuvant to Ropivacaine 0.375% in adductor canal block: Dexamethasone 4mg is added to 20 mL Ropivacaine 0.375% in USG guided adductor canal for post operative an

Sponsors

Bangalore Medical College and Research Institute
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade I and II. Patients undergoing reconstructive and replacement Surgeries of knee under spinal Anaesthesia

Exclusion criteria

Exclusion criteria: Patient not willing to give informed written consent. Significant psychiatric or mental disorder . Lower extremity neuropathy or neurological deficit. Coagulopathy Local skin infections . Allery to local anaesthetics and dexmeditomidine

Design outcomes

Primary

MeasureTime frame
To assess post operative analgesia by Visual Analogue Scale after surgery upto 24 hoursTimepoint: To assess post operative analgesia by Visual Analogue Scale after surgery upto 24 hours—

Secondary

MeasureTime frame
To assess Quadriceps muscle strength using Medical Research Council Grading for muscle strengthTimepoint: To assess muscle strength using Medical Research Council Grading at 1 hr,6 hrs,12 hrs,18 hrs , 24 hrs;Time for first dose of rescue analgesiaTimepoint: Time of requirement for first dose of Tramadol 50 mg intravenous injection;To assess haemodynamic parameters Heart rate,Systemic blood pressure, Diastolic blood pressure,SpO2 , respiratory rateTimepoint: To assess haemodynamic parameters at immediately,15 minutes,30 minutes,45 minutes ,1 hrs, 6 hrs,12 hrs 18 hrs 24 hrs—

Countries

India

Contacts

Public ContactDR MARULASIDDESHWARA C R

Bangalore Medical College and Research Institute Bangalore

Marulasiddesh31@gmail.com9916070299

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026