Comparing Two Types of Anaesthesia (with and without Opioids) for patients undergoing keyhole Abdominal Surgeries.

Opioid-free (OFA) versus Opioid-based(OBA) Anaesthesia in Laparoscopic Abdominal Surgeries:A Prospective Randomized Controlled Trial - OFA and OBA

Status

Active, not recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/085212

Enrollment

Registered

2025-04-21

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K800- Calculus of gallbladder with acutecholecystitis

Interventions

Intervention1: Opioid Free Anaesthesia(OFA): Induction done with- Dexmedetomidine: Loading dose of 0.6 g/kg over 10 minutes, followed by a maintenance infusion of 0.5 g/kg/h. Ketamine: Bolus of 0.5

Eligibility

Inclusion criteria

Inclusion criteria: 1. Adult aged 18 years and older undergoing laparoscopic abdominal surgeries. 2. ASA classification I-II .3. Patients capable of providing informed consent or with consent provided by legal guardian

Exclusion criteria

Exclusion criteria: 1.Patients with contraindications or allergies to study medications. 2.Patients with chronic opioid use or opioid dependence. 3. Pregnant or lactating women. 4.Patients refusal.

Design outcomes

Primary

Measure	Time frame
To compare postoperative pain scores in both groups by using Numeric Rating Scale(NRS).Timepoint: At immediate postop, 06 hours,12 hours,24 hours postoperatively.	—

Secondary

Measure	Time frame
To determine analgesic requirement within first 24 hours. Time to first analgesic request Incidence of postoperative nausea and vomiting Sedation scores(RASS Scale) and patient satisfaction.Timepoint: At 06 hours , 12hours , 24 hours postoperatively.	—

Countries

India

Contacts

Public ContactBhavna Hooda

Army Hospital Research and Referral

drbhavnahooda@gmail.com9910663810

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026