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Exosomes Eye Drops

Exosomes based eye drops for corneal repair after transplantation - NIL

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/085199
Enrollment
10
Registered
2025-04-21
Start date
Unknown
Completion date
Unknown
Last updated
2026-01-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H188- Other specified disorders of cornea

Interventions

Intervention1: Exosomes fortified CMC Eye Drops: Readily Available Carboxymethyl cellulose eye drops will be fortified with pure exosomes(10%)and will be used to study role of exosomes in failed corne

Sponsors

Santosh Deemed to be university
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Corneal graft Failure all available medical therapy have failed Invariably accompanied by low vision due to opacified central cornea

Exclusion criteria

Exclusion criteria: patients with other ocular diseases patients not willing to give consents

Design outcomes

Primary

MeasureTime frame
EXPLORING THERAPEUTIC POTENTIAL OF EXOSOME BASED EYE DROPS (CMC DROPS FORTIFIED WITH EXOSOMES)Timepoint: 3 months 6 months 9 months

Secondary

MeasureTime frame
Understanding Immune modulation in the context of corneal transplantation. Novel insights into the pathophysiology of graft failureTimepoint: Baseline-At the start of study(0 days) 8 days-Assesment and 16 days-Assesment

Countries

India

Contacts

Public ContactDr Sarita Aggarwal

Santosh Medical College and Hospital

sarita.doctor@gmail.com09810972539

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026