A Comparative Study Between Intravenous Inj. Dexmeditomidine and Inj. Labetalol for Preventing Hemodynamic Responses During Intubation in ENT Surgeries

Intravenous Dexmedetomidine Versus Labetalol in Attenuating Pressor Response To Laryngoscopy And Tracheal Intubation In Patients Undergoing Otorhinolaryngology Surgeries Under General Anesthesia. A Prospective Randomized Controlled Trail - nil

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/085181

Enrollment

162

Registered

2025-04-21

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: H661- Chronic tubotympanic suppurative otitis media Health Condition 2: O- Medical and Surgical Health Condition 3: H75- Other disorders of middle ear andmastoid in diseases classified elsewhere

Interventions

Intervention1: HEMODYNAMIC PRESSOR RESPONSE: To evaluate the effectiveness of intravenous Dexmedetomidine vs Labetalol in attenuating the hemodynamic pressor response to laryngoscopy and tracheal intu

Eligibility

Inclusion criteria

Inclusion criteria: Age between 18yrs-60yrs. ASA I and II patients. Patients with MPG- I & II. Surgeries lasting approximately 120-180 minutes

Exclusion criteria

Exclusion criteria: Patients refusal. Patients allergy to study drug. Patients of uncontrolled hypertension and tachycardia

Design outcomes

Primary

Measure	Time frame
To evaluate the effectiveness of intravenous Dexmedetomidine vs Labetalol in attenuating hemodynamic pressor response to laryngoscopy and tracheal intubation.Timepoint: 1 hour	—

Secondary

Measure	Time frame
To provide hypotensive anesthesia and bloodless surgical fields Timepoint: 2 hours	—

Countries

India

Contacts

Public ContactDR G MANUJKUMAR

AARUPADI VEEDU MEDICAL COLLEGE AND HOSPITAL

ezhilrajan96@gmail.com9843030074

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026