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Comparing Platelet rich fibrin,Low level laser therapy and combination of platelet rich fibrin and low level laser therapy in periapical lesion healing.

Comparative evaluation of efficacy of PRF,Low Level Laser Therapy and PRF+Low Level Laser Therapy on healing of periapical lesion - NIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/085172
Enrollment
27
Registered
2025-04-21
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K047- Periapical abscess without sinus

Interventions

Intervention1: Low level laser therapy: Low level laser therapy using Gallium-Aluminium-Arsenide soft tissue diode laser of 980nm .It is applied on inner and outer side of the flap of periapical osseo

Sponsors

Meenakshi K
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with age group 20-40 years of either gender Periapical lesions involving maxillary incisors of strictly endodontic origin. Root canal treated maxillary incisors with persistent periapical infections. PAI Score 5+D Patients who are willing for voluntary participation & who have signed informed consent Patients with good oral hygiene. Systemically healthy patients

Exclusion criteria

Exclusion criteria: Periodontally compromised teeth with poor prognosis Tooth with pathosis associated with vertical root fracture Patients with bleeding disorders. Patients with poor oral hygiene Patients with use of tobacco or tobacco related products Pregnant / Lactating patients Patients with systemic diseases Patients with any known allergies Patients with any known metabolic disorders

Design outcomes

Primary

MeasureTime frame
Bone Regeneration in periapical lesionTimepoint: six months and twelve months

Secondary

MeasureTime frame
soft tissue hesling of periapical lesion and periapical lesionTimepoint: 1st,3rd,5th,7th day

Countries

India

Contacts

Public ContactDR RAMAPRABHA B

Tamilnadu government dental college and hospital

isharamah@gmail.com9940666344

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026