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Understanding Genetic Risk for Malocclusion How FGF and ESR Genes Influence Orthodontic Outcomes

Genetic risk profiling for malocclusion the predictive role of FGF AND ESR gene in orthodontic patients - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/04/085120
Enrollment
27
Registered
2025-04-21
Start date
Unknown
Completion date
Unknown
Last updated
2025-05-26

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K088- Other specified disorders of teethand supporting structures

Interventions

Intervention1: Nil: Nil

Sponsors

Abhishek
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Complete eruption of the permanent dentition up to the first molar. Patients exhibiting Angle s Class I malocclusion. Individuals with normal dental morphology and proportionate tooth dimensions

Exclusion criteria

Exclusion criteria: Severe craniofacial anomalies or prior orthodontic interventions that may compromise measurement validity. Pre-existing Class I or II or III dental restorations and interproximal carious lesions Extensive occlusal attrition, presence of peg shaped lateral incisors and supernumerary teeth Marked dental malalignment impeding accurate measurements or exclusion due to poor-quality or fractured dental casts Patient diagnosed with Angles Class II or Class III malocclusion

Design outcomes

Primary

MeasureTime frame
changes produced in the DNA sequence of FGF and ESR group in the case of tooth size and arch length discrepanciesTimepoint: at baseline—

Secondary

MeasureTime frame
To find the relation of these genes with arch length & the tooth sizeTimepoint: at baseline—

Countries

India

Contacts

Public ContactDr Deepti Yadav

Inderprastha dental college and hospital

deepti.yadav@yahoo.com9212794482

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026