Health Condition 1: C148- Malignant neoplasm of overlappingsites of lip, oral cavity and pharynx
Conditions
Interventions
Intervention1: NIL: NIL
Control Intervention1: NIL: NIL
Sponsors
Department of Anaesthesiology and Critical Care , K.S HEGDE MEDICAL ACADEMY
Eligibility
Inclusion criteria
Inclusion criteria: 1 Patients with confirmed diagnosis of head and neck cancer. 2 Patients belonging to ASA grade I II and III
Exclusion criteria
Exclusion criteria: 1 Patient refusal. 2 Patients with previous severe adverse reaction to Pregabalin and Gabapentin. 3 Patients with renal impairment. 4 Patients already on opioids. 5 Patients taking Gabapentin or Pregabalin for other medical purposes.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the intensity of pain among the two groups in the postoperative period, i.e., at 1hr, 2hr, 4hr, 6hr, 12hr and 24hr Time for first rescue analgesic.Timepoint: Group G: Gabapentin capsule 600 mg Group PG: Pregabalin capsule 150 mg with sips of water 1 hour before the expected time of induction of anaesthesia. | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative nausea & vomiting (PONV). Dizziness Sedation in the first 24 hours postoperatively. Timepoint: The total dose of rescue analgesic needed in the first 24 h of the postoperative period will be recorded. The sedation score will be assessed by the Ramsay sedation assessment scale. Any side effects such as dizziness, nausea, vomiting, headache & respiratory depression will be noted. | — |
Countries
India
Contacts
Public ContactGAYATHRI BHAT
K.S HEGDE MEDICAL ACADEMY
Outcome results
None listed