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Effectiveness of Pain relief after tooth extraction using hydroxyapatite as a local placement of bupivacaine or saline in the socket.

Controlled Local Drug Delivery of Bupivacaine in Maxillary and Mandibular Extraction Sockets using Hydroxyapatite as a carrier: A Triple -Blinded Randomized Controlled Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/085039
Enrollment
42
Registered
2025-04-17
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: Hydroxyapatite with Bupivacaine: to evaluate the effectiveness of controlled drug delivery of a local anesthetic placed in the extraction socket, using hydroxyapatite as the carrier, w

Sponsors

Anugu Anjali
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients above 18 years old and healthy patients. 2.Patients who presented to the OPD of Department of Oral and Maxillofacial Surgery of Sri Ramachandra Institute of Higher Education and Research. 3.Patients with the need of Maxillary and Mandibular posterior teeth extraction procedure with no reported history of allergic reactions to the local anesthetic agents used in the study. 4.Patients who were willing for investigations and treatment procedure.

Exclusion criteria

Exclusion criteria: 1.Patients with systemic diseases, pregnant females. 2.Patients with impacted teeth due to any pathology, such as cysts or tumors. 3.Patients presenting with signs and symptoms of acute general infections, such as fever and lymphadenopathy. 4.Patients who had taken any type of analgesic within 24h prior to the extraction. 5.Patients who were not willing for further investigations and treatment.

Design outcomes

Primary

MeasureTime frame
To evaluate the effectiveness of controlled drug delivery of a local anesthetic using hydroxyapatite.Timepoint: 6,12 and 24th hour

Secondary

MeasureTime frame
To evaluate Pain score using Visual Analogue Pain ScoreTimepoint: 6, 12 and 24th hourly

Countries

India

Contacts

Public ContactAnugu Anjali

Sri Ramachandra Institute of Higher Education and Research

naveenkumarj@sriramachandra.edu.in9100653748

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026