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Centhaquine as a resuscitative agent in trauma

An observational study of centhaquine as a resuscitative agent in hemorrhagic shock due to trauma - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2025/04/085034
Enrollment
75
Registered
2025-04-17
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: T07- Unspecified multiple injuries

Interventions

Control Intervention1: NIL: NIL

Sponsors

Medanta the Medicity
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Trauma patients with SBP less than 90mmHg Trauma patients with Blood Lactate greater than equal to 2 mmol per Liter Trauma patients with age greater than 18 years

Exclusion criteria

Exclusion criteria: 1. Hypovolemia due to causes other than trauma 2. Presence of any other terminal illness not associated with haemorrhagic shock during the study duration. 3. Cardiopulmonary resuscitation (CPR) before enrolment 4. Pregnancy 5. Patients received blood or blood products before coming to emergency. 6. Obstructive shock – cardiac tamponade / tension pneumothorax.

Design outcomes

Primary

MeasureTime frame
Improvement in systolic blood pressure greater than or equal to 90mmHg and decrease in blood lactates in VBG to more than 25 percent of initial value with Centhaquine in patients with hemorrhagic shock due to traumaTimepoint: 1 hour

Secondary

MeasureTime frame
Need of blood and blood products after giving Centhaquine in 48 hours Measure the urine output in 48 hours after giving Centhaquine Timepoint: 48 hours

Countries

India

Contacts

Public ContactDr Shruti Bansal

Medanta the Medicity

Shrutibansalin@yahoo.com8130893335

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026