Health Condition 1: - Health Condition 2: O- Medical and Surgical
Conditions
Interventions
Intervention1: continuous intravenous sedation in post operative mechanically ventilated patients with ketamine dexmedetomidine combination: Post operative patients shifted to ICU for elective mechani
Sponsors
Pt B D Sharma PGIMS
Eligibility
Inclusion criteria
Inclusion criteria: 1)Post operative patients between 18-60 years of age, intubated and shifted to ICU for a period of 12 to 24 hours 2)Afebrile 3)Hemodynamically stable
Exclusion criteria
Exclusion criteria: 1)Pateint less than 18 years of age 2)patient with hypotension, Bradycardia, metabolic acidosis. 3)patients with head injury 4)patients requiring neuromascular blocking agents along with sedation 5)pregnancy 6)neurological disease or injury 7)liver or renal insufficiency 8)intraoperative or post operative hemodynamic instability 9)patients on vasopressor or ionotropic support 10)patients with metabolic derangements 11)patients receiving epidural or any other type of analgesia apart from the standardized analgesia used in study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1)modified RASS score 2)Nonverbal pain score 3)adverse effectsTimepoint: 1)Modified RASS score will be assessed at starting of infusion(0hr),1Hr,6Hr,12hr and 24hrly 2)nonverbal pain score will be assessed at starting of infusion(0hr),1hr,6hr,12hr and 24hr 3)adverse effects will be assessed at any time during continuous intravenous infusion | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)Recovery time 2)duration of weaningTimepoint: R time of stopping of infusion [T1] to time of return of full consciousness[T2] is recovery time will be assessed after stopping of infusion. 2)duration of weaning is that Time of start of spontaneous breathing trial[T3] to time of extubation [T4] | — |
Countries
India
Contacts
Public ContactDr Vignesh P
Department of Anaesthesiology and Critical care
Outcome results
None listed