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Effect of 0.2 percent Chitosan and 970nm Diode laser on Post-Operative pain in single visit root canal treatment

Effect of 0.2% Chitosan and 970nm diode laser disinfection on post-operative pain after single visit endodontic therapy: A Randomized Clinical Trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/084995
Enrollment
90
Registered
2025-04-16
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: B998- Other infectious disease Health Condition 2: B968- Other specified bacterial agents as the cause of diseases classified elsewhere Health Condition 3: K040- Pulpitis

Interventions

Intervention1: 0.2 percent Chitosan Irrigant: 0.2 percent Chitosan derived from naturally occuring polysaccharide chitin used as a root canal irrigant for removal of inorganic smear layer during the R

Sponsors

Dr Vidula Jain
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients requiring root canal treatment of mandibular premolar teeth with single root canal, diagnosed clinically as asymptomatic irreversible pulpitis using pulp sensitivity tests 2. Patients ranging in the age group of 18-50 years 3. Patients with non-contributory medical history 4. Teeth with no pre-operative pain 5. Teeth with adequate coronal structure to ascertain proper isolation

Exclusion criteria

Exclusion criteria: EXCLUSION CRITERIA: PATIENT SPECIFIC: 1.Patients who refuse to consent for the procedure. 2.Patients with any systemic diseases, pregnancy or immuno-compromised conditions. 3.Patients on any antibiotic therapy in the past 3 months 4.Patients on any analgesic drugs in the past 7 days 5.Patients allergic to lignocaine in 1:100,000 concentration adrenaline 6.Patients requiring root canal treatment of two or more teeth ipsilaterally (since the pain caused by any of these teeth can result in false positive reading) SPECIFIC TO DIAGNOSIS: 1.Teeth with acute apical periodontitis 2.Teeth with acute periapical abscess 3.Teeth with an inflammatory exudate draining through the canal. 4.Necrotic painful teeth with absence of sinus tract for drainage 6.Re-treatment cases 7.Teeth with aggressive periodontitis or grade III mobility TOOTH SPECIFIC: 1.Teeth with calcified canals, immature apex and internal and external resorption. 2.Severe labially or lingually mal-positioned teeth in which obtaining straight line access is difficult

Design outcomes

Primary

MeasureTime frame
To assess the effect of 0.2% Chitosan disinfection on post operative pain after single visit endodontics using Visual Analogue Scale 2. To assess the effect of 970nm Diode Laser disinfection on post operative pain after single visit endodontics using Visual Analogue Scale 3. To compare the effect of 0.2% Chitosan and 970nm Diode Laser disinfection on post operative pain after Single Visit Endodontics usingTimepoint: 6 hours, 24 hours, 48 hours and 72 hours post operatively—

Secondary

MeasureTime frame
To evaluate and compare the association of variables (age and sex) between groupsTimepoint: 6, 24, 48 and 72 hours—

Countries

India

Contacts

Public ContactDr Anand C Patil

K.L.E.V.K Institute of Dental Sciences

vidulajain34@gmail.com9158336383

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026