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Evaluation of antimicrobial property of probiotic toothpaste and probiotic mouthwash

A Comparison of Efficacy of Probiotic Toothpaste and Probiotic Mouthwash to Reduce Streptococcus Mutans in Plaque Around Orthodontic Brackets: An In Vivo Study - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/084988
Enrollment
54
Registered
2025-04-16
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: probiotic toothpaste: toothpaste in which probiotics are added Intervention2: probiotic mouthwash: mouthwash in which probiotics are added Control Intervention1: Control Group: normal T

Sponsors

Dr Jainil Patel
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients who received fixed orthodontic treatment for at least three months. 2.No systemic illnesses like diabetes mellitus or immunological diseases like AIDS Healthy periodontium

Exclusion criteria

Exclusion criteria: Composite restorations and prosthetic crowns on anterior teeth Patients with Oral Hygiene Index-Simplified (OHI-S) score more than 3 Teeth with developmental anomalies or fluorosis Patients on medication like phenytoin, or immunosuppressants Need for anti-inflammatory or antibiotic medication Pregnant women and smokers History of frequent vomiting

Design outcomes

Primary

MeasureTime frame
Compare antimicrobial property of probiotic mouthwash and probiotic toothpasteTimepoint: at baseline and at 4 weeks—

Secondary

MeasureTime frame
NILTimepoint: NIL—

Countries

India

Contacts

Public ContactDr Jainil Patel

Manubhai Patel Dental College & Hospital

padmaja2216@yahoo.co.in9033975429

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026