Comparison of Amniotic Membrane and T-PRF in Treating Gum Recession Using a Coronally advanced Flap Surgery Technique

Comparative evaluation of Amniotic membrane versus T PRF as a soft tissue regenerative material in the microsurgical management of Cairo s RT 1 & RT 2 in isolated gingival recession using coronally advanced flap technique A randomized split mouth clinical study - AMTPRF-GR-TRIAL

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2025/04/084986

Enrollment

Registered

2025-04-16

Start date

Unknown

Completion date

Unknown

Last updated

2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K056- Periodontal disease, unspecified

Interventions

Intervention1: T-PRF: As soft tissue regenerative material Control Intervention1: Amniotic Membrane: As soft tissue regenerative material

Eligibility

Inclusion criteria

Inclusion criteria: RT1 and RT2 Gingival recession

Exclusion criteria

Exclusion criteria: Patients with co morbidities, bone loss , wasting diseases

Design outcomes

Primary

Measure	Time frame
Significant difference between Amniotic Membrane and T-PRF as soft tissue regenerative material improving mean root coverageTimepoint: 90th day and 180th day	—

Secondary

Measure	Time frame
Wound healing index , Gingival thicknessTimepoint: 90th day and 180th day	—

Countries

India

Contacts

Public ContactDevadharshini C

Meenakshi Ammal Dental College

drburnice.perio@madch.edu.in9790944335

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026