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Comparison between two drugs d during insertion of a device

A clinical comparative study of etomidate and propofol plus ketamine as an induction agent on quality of proseal laryngeal mask airway insertion and hemodynamic stability in patients undergoing laparoscopic cholecystectomy - Nil

Status
Active, not recruiting
Phases
Phase 2Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/084977
Enrollment
92
Registered
2025-04-16
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O- Medical and Surgical

Interventions

Intervention1: Comparison of drugs in inserting Proseal laryngeal mask airway insertion: Two groups will be made Group A - will be given etomidate 0.3mg/kg without muscle relaxant before insertion of

Sponsors

Lala Lajpat rai medical college,Meerut, UP
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade I and II Age 18 to 65 years of either sex Patient undergoing laparoscopic cholecystectomy Patient with informed consent MPG I and II

Exclusion criteria

Exclusion criteria: Patient refusal Patient with history gastroesopheal disease Patient with cardiac disease, lung disease,alcholism,morbid obesity,pregnancy,any abnormality of oral cavity or pharynx or patient prone for pulmonary complications like COPD, Pneumonia ASA III,IV,V Patient undergoing emergency surgery Patients with uncontrolled hypertension,uncontrolled diabetes,previous history of stroke Cervical spine fracture or instability Morbid obese patient

Design outcomes

Primary

MeasureTime frame
To see the effectiveness of insertion and establishment of airway with Proseal larynseal mask airway on induction with etomidate and propofol plus ketamine in patient undergoing laparoscopic cholecystectomy. Comparison of effectiveness of the induction agents for adequate relaxation for inserting PLMA Time for successful insertionTimepoint: 1 minutes, 3 minutes 5 minutes 15 minutes 30 minutes

Secondary

MeasureTime frame
Oropharyngeal leak pressure,sore throat Ease and required attempts for proseal laryngeal mask airway insertion. Quality of airway with controlled ventilation during maintenance of anaesthesia. Complications Hemodynamic stability of induction agents Timepoint: 1min, 3min, 5min, 15min, 30min

Countries

India

Contacts

Public ContactDr Jyotiraj sahoo

LALA LAJPAT RAI MEDICAL COLLEGE,MEERUT ,UP

anaesthesiadeptt@gmail.com9634857368

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026