FindTrial
Sign In

To find the effectiveness of natural extracts in enhancing bonding between tooth and restorative material

Assessment of the effectiveness of Quercetin as dentin biomodifier on resin-dentin interface of permanent mandibular molars - A split mouth randomised clinical trial - NIL

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/084971
Enrollment
50
Registered
2025-04-16
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K025- Dental caries on pit and fissure surface

Interventions

Intervention1: 1% quercetin: Quercetin most common flavonol (70%) is present in onions, tea, apples. It offers several benefits including anti-inflammatory, antioxidant.Could be a promising additive

Sponsors

DR SAQLAIN SHUAIB S A
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Good general health Acceptable oral hygiene Atleast 20 teeth under occlusion Class 1 dental caries in permanent mandibular molars Cavity depth 1 to 2mm

Exclusion criteria

Exclusion criteria: Non vital teeth Temporomandibular dysfunction Spontaneous acute pain Periodontal disease Presence of mobility and hypoplasia

Design outcomes

Primary

MeasureTime frame
Effectiveness of 1.0 wt % Quercetin as dentin biomodifier on resin-dentin interfaceTimepoint: Baseline,3rd month and 6th month—

Secondary

MeasureTime frame
Marginal adaptation , postoperative sensitivtyTimepoint: baseline,third month, sixth month—

Countries

India

Contacts

Public ContactDR SAQLAIN SHUAIB S A

Karpaga Vinayaga Institute of Dental Sciences

v.naveenmds@gmail.com9884328813

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026