Skip to content

The effect of local placement of vitamin E in reducing post operative pain during multiple lower jaw teeth removal

The effect of intra-socket Vitamin E placement in reducing dry socket occurance and postoperative pain in multiple mandibular extractions: A split-mouth triple blinded randomized control trial - NIL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2025/04/084961
Enrollment
59
Registered
2025-04-16
Start date
Unknown
Completion date
Unknown
Last updated
2025-04-28

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: K040- Pulpitis

Interventions

Intervention1: VITAMIN E: A gel foam will be cut into 1x1 cm and soaked in Vitamin E 40 IU soft gels (manufactured by Procter and Gamble Health Ltd under the trade name - Evion) squeezed out and packe

Sponsors

ANAMIKA K S
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Males and females aging 20 to 40. (to ensure that none of the post-menopausal since oestrogen and progesterone are important variables of dry socket) Patients with need of bilateral mandibular teeth extractions. Complaince with all requirements in the study and signing the informed consen.

Exclusion criteria

Exclusion criteria: Patients with systemic diseases that may affect the outcomes of the study such as uncontrolled diabetes, hyperthyroidism , hyperparathyroidism, paget’s disease also diseases affecting bone healing , includes osteoporosis ,rickets ,and osteomalacia . Patients on chronic medications affecting the periodontal status such as anticonvulsant , calcium channel blockers ,immunosuppressive , anti-inflammatory medications. Pathological lesions at the site of impaction. Patients with history of smoking , alcohol consumption, lactating mothers. Patients currently on radiotherapy and or chemotherapy.

Design outcomes

Primary

MeasureTime frame
Post operative pain evaluation is done using visual analog scale and overall healing is evaluated using Laundry et al. The assessment was done for the presence or absence of signs and symptoms of dry socket including halitosis, foul taste, socket devoid of clot with exposed bone that may be filled with food debris, edema of the surrounding gingiva, and regional lymphadenitis.Timepoint: 3rd , 7th , 14th post operative day

Secondary

MeasureTime frame
Symptomatic relief and reduced rate of post operative complicationTimepoint: 3rd, 7th , 14th post operative day

Countries

India

Contacts

Public ContactANAMIKA K S
pearlcid@hotmail.com9791116178

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026